1.
Acta gastroenterol. latinoam
;
33(4): 183-185, 2003. tab
Article
in Spanish
| LILACS
| ID: lil-359981
ABSTRACT
In randomized groups of Wistar rats, the effect inhibitor of selective NASAID over the COX-1, COX-2 and COX-3 the synchronizes inhibition of COX-1 and COX-2, COX-1 and COX-3, COX-2 and COX-3, and COX-1, COX-2 and COX-3 were studied. The conclusions were that the selective inhibition of COX-1, COX-2 and COX-3 no given gastrointestinal damage; the synchronizes inhibition of COX-1 and COX-2 given preferential gastric damage; in contrast the inhibition of COX-2 and COX-3 given massive necrosis preferential in small intestine.
Subject(s)
Animals , Female , Rats , Anti-Inflammatory Agents, Non-Steroidal/adverse effects , Cyclooxygenase Inhibitors , Gastrointestinal Tract/drug effects , Isoenzymes/antagonists & inhibitors , Gastrointestinal Diseases/chemically induced , Gastrointestinal Diseases/enzymology , Gastrointestinal Tract/enzymology , Gastrointestinal Tract/pathology , Prostaglandin-Endoperoxide Synthases
2.
Indian J Exp Biol
;
1979 May; 17(5): 507-9
Article
in English
| IMSEAR
| ID: sea-57722
3.
J Indian Med Assoc
;
1972 Jan; 58(1): 6-9
Article
in English
| IMSEAR
| ID: sea-103706